Description

3-[3-(Carbamoylmethyl)-2,4,6-Triiodo-Phenyl]Propanoic Acid is a high-purity, triiodinated organic compound primarily used as a key intermediate in the synthesis of iodinated contrast media. Its precise molecular structure is critical for ensuring the efficacy and safety of the final pharmaceutical products. This compound is essential for manufacturers in the pharmaceutical and diagnostic imaging industries requiring reliable, high-quality building blocks for complex X-ray and CT scan contrast agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of non-ionic, iodinated X-ray contrast agents such as Iopamidol, Ioversol, and Iopromide.
• Diagnostic Imaging: Serves as a precursor for agents used in computed tomography (CT), angiography, and urography to enhance vascular and organ visualization.
• Research & Development: Used in academic and industrial R&D for developing new contrast media with improved safety profiles and imaging characteristics.
• Fine Chemical Synthesis: Employed in specialized organic synthesis routes requiring a highly functionalized, triiodinated aromatic core.

Basic Information

Item	Details
Product Name	3-[3-(Carbamoylmethyl)-2,4,6-Triiodo-Phenyl]Propanoic Acid
CAS No.	1456-51-5
Molecular Formula	C11H9I3N1O3
Molecular Weight	585.91 g/mol
Synonyms	5-Acetamido-2,4,6-triiodoisophthalic Acid 1-Methylamide; 5-(Acetylamino)-2,4,6-triiodo-1,3-benzenedicarboxylic Acid 1-Methylamide; ATIPA; NSC 82100; 3-[3-(Carbamoylmethyl)-2,4,6-triiodophenyl]propanoic acid; 5-Acetamido-2,4,6-triiodoisophthalamic Acid N-Methyl Ester (related derivative)
EINECS	Contact for details

Quality Control

Our 3-[3-(Carbamoylmethyl)-2,4,6-Triiodo-Phenyl]Propanoic Acid is manufactured under strict quality management systems. We provide material suitable for pharmaceutical intermediate synthesis, with quality controls aligned with ICH guidelines. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.