Description

[4aS-[4aα,6α,8aα,8bβ,10aα,11α(1S*,2E,4R*),13aβ,13bα]]-5,6,7,8,8a,8b,10,10a,11,12,13,13a-Dodecahydro-6-hydroxy-8a,10a-diMethyl-2-phenyl-11-[1,4,5-triMethyl-5-[(tetrahydro-2H-pyran-2-yl)oxy]-2-hexenyl]-4a,13b-etheno-1H,9H-benzo[c]cyclopenta[h][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione is a complex, high-purity synthetic organic compound characterized by its intricate polycyclic structure. This compound serves as a critical advanced intermediate in sophisticated organic synthesis, particularly for research and development in pharmaceutical discovery. It is essential for chemists and organizations engaged in developing novel active pharmaceutical ingredients (APIs), complex natural product analogs, and specialized fine chemicals.

Application

• Pharmaceutical Research & Development (R&D): A key building block for the synthesis of novel drug candidates, especially in therapeutic areas requiring complex molecular architectures.
• Advanced Organic Synthesis: Used as a sophisticated intermediate in multi-step synthetic routes for complex natural products and their derivatives.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the development of molecular probes.
• Process Chemistry Development: Serves as a reference standard or intermediate for scaling up synthetic pathways from laboratory to pilot plant scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in synthetic methodology and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	[4aS-[4aα,6α,8aα,8bβ,10aα,11α(1S*,2E,4R*),13aβ,13bα]]-5,6,7,8,8a,8b,10,10a,11,12,13,13a-Dodecahydro-6-hydroxy-8a,10a-diMethyl-2-phenyl-11-[1,4,5-triMethyl-5-[(tetrahydro-2H-pyran-2-yl)oxy]-2-hexenyl]-4a,13b-etheno-1H,9H-benzo[c]cyclopenta[h][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione
CAS No.	170716-87-7
Molecular Formula	C44H55N3O5
Molecular Weight	705.93 g/mol
Synonyms	Benzo[c]cyclopenta[h][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione derivative; CAS 170716-87-7; Complex polycyclic triazolocinnoline; THP-protected polycyclic intermediate; Advanced pharmaceutical intermediate (API Intermediate); Polycyclic fused triazole derivative; High molecular weight heterocycle.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with each shipment, typically including results from HPLC, NMR, and mass spectrometry. Our quality protocols are designed to meet the exacting standards required for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be incompatible with strong acids and organic solvents; store separately from such materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.