Description

5-Thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, (6R,7R)- is a high-purity, non-natural cephalosporin derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chemical reference standard and a sophisticated pharmaceutical intermediate for the synthesis of novel antibacterial agents. It is essential for researchers and manufacturers in the pharmaceutical industry focused on developing next-generation antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of advanced cephalosporin antibiotics.
• Chemical Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related drug substances and products.
• Antibacterial Research: Serves as a core structure in medicinal chemistry programs aimed at discovering new antibacterial agents with improved spectra and potency.
• Process Chemistry Development: Utilized in scaling up and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs).
• Impurity Profiling: Employed as a marker or standard to identify and quantify related substances in cephalosporin APIs.

Basic Information

Product Name	5-Thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, (6R,7R)-
CAS No.	145904-68-3
Molecular Formula	C20H20N6O5S2
Molecular Weight	488.54 g/mol
Synonyms	(6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(Z)-2-(4-methylthiazol-5-yl)vinyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefcapene Pivoxil Intermediate; Cefcapene Impurity; Cefcapene Related Compound; 7-ACA Derivative; Advanced Cephalosporin Intermediate; (6R-cis)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 5-Thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support development and regulatory needs with materials suitable for use as pharmaceutical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.