Description

(7R)-3-[[(1,3,4-Thiadiazol-2-yl)thio]methyl]-7-formylamino-7β-[[(4-hydroxyphenyl)[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]acetyl]amino]cepham-3-ene-4-carboxylic acid sodium salt is a high-purity, advanced pharmaceutical intermediate belonging to the cephalosporin class of β-lactam antibiotics. This compound is critical for the synthesis of next-generation, broad-spectrum antibiotics designed to combat resistant bacterial strains. It is primarily required by pharmaceutical R&D laboratories and API (Active Pharmaceutical Ingredient) manufacturers engaged in developing novel anti-infective therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced cephalosporin antibiotics.
• Antibiotic R&D: Used in research and development of new antibacterial agents with enhanced efficacy against resistant pathogens.
• API Manufacturing: Serves as a critical precursor in the production scale-up of final active pharmaceutical ingredients.
• Structure-Activity Relationship (SAR) Studies: Utilized in medicinal chemistry to explore modifications for optimizing pharmacokinetic and pharmacodynamic properties.
• Reference Standard: Can be used as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	(7R)-3-[[(1,3,4-Thiadiazol-2-yl)thio]methyl]-7-formylamino-7β-[[(4-hydroxyphenyl)[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]acetyl]amino]cepham-3-ene-4-carboxylic acid sodium salt
CAS No.	137624-13-6
Molecular Formula	C27H26N8O8S3Na
Molecular Weight	717.73 g/mol
Synonyms	Sodium (7R)-3-[[(1,3,4-thiadiazol-2-yl)thio]methyl]-7-formylamino-7β-[[(4-hydroxyphenyl)[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]acetyl]amino]cepham-3-ene-4-carboxylate; Cephalosporin derivative intermediate; 137624-13-6; Sodium cephem derivative; Advanced cephalosporin synthon
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles. We adhere to strict quality management protocols suitable for pharmaceutical intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.