Description

7-((N(5)acetyl-N(5)-hydroxyornithyl-N(5)acetyl-N(5)hydroxyornithyl-N(5)-acetyl-N(5)-hydroxyornithyl-4-hydroxyphenylglycyl)amino)-3-chloro-1-carba-3-cephem-4-carboxylic acid is a sophisticated synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound is a key building block in the synthesis of novel carbacephem antibiotics, a class designed for enhanced stability and activity against resistant bacterial strains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and production of next-generation anti-infective agents.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthetic pathway for novel carbacephem and β-lactam antibiotic candidates.
• Antibiotic Research & Development: Serves as a key scaffold for structure-activity relationship (SAR) studies to develop new antimicrobial agents with improved efficacy.
• Process Chemistry & Scale-Up: Used in the development and optimization of commercial-scale manufacturing processes for advanced antibiotic APIs.
• Biochemical Research: Employed in studies investigating bacterial cell wall synthesis and the mechanisms of β-lactam resistance.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical production.

Basic Information

Product Name	7-((N(5)acetyl-N(5)-hydroxyornithyl-N(5)acetyl-N(5)hydroxyornithyl-N(5)-acetyl-N(5)-hydroxyornithyl-4-hydroxyphenylglycyl)amino)-3-chloro-1-carba-3-cephem-4-carboxylic acid
CAS No.	124620-50-4
Molecular Formula	C41H56ClN9O17
Molecular Weight	982.39 g/mol
Synonyms	Loracarbef Intermediate; 3-Chloro-7-[(2-(2-amino-4-hydroxy-4-oxobutyl)-2-hydroxy-3-(2-(2-hydroxy-3-(2-(2-hydroxy-3-(4-hydroxyphenyl)-1-oxopropyl)amino)-1-oxopropyl)amino)-1-oxopropyl)amino]-1-carba-1-dethia-3-cephem-4-carboxylic Acid; Carbacephem Derivative; Antibiotic Synthesis Intermediate; (6R,7S)-7-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-[(Carboxycarbonyl)amino]-2-[(4-hydroxyphenyl)formamido]butanoyl]amino]-4,5-dihydroxy-5-oxopentanoyl]amino]-4,5-dihydroxy-5-oxopentanoyl]amino]-4,5-dihydroxy-5-oxopentanoyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to stringent cGMP (current Good Manufacturing Practice) guidelines to ensure batch-to-batch consistency and traceability. Every lot undergoes comprehensive analytical testing, including HPLC purity assay, chiral purity verification, and identification by spectroscopic methods (IR, NMR). A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.