Description

Ristomycin A aglycone, 34-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-2-deoxy-2-(10-methyl-1-oxoundecyl)amino-β-D-glucopyranosyl-42-O-α-D-mannopyranosyl- is a complex, semi-synthetic glycopeptide derivative of the ristomycin family. This compound is of significant interest for its role as a key intermediate in advanced pharmaceutical research and development, particularly in the study of novel antibacterial agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis and evaluation of next-generation antibiotics targeting resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthetic pathway for novel glycopeptide antibiotics.
• Antibacterial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) against Gram-positive bacteria.
• Mechanism of Action Studies: Employed in research to elucidate the binding mechanisms of complex antibiotics to bacterial cell wall precursors.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: Utilized in the design and synthesis of analogs to improve pharmacokinetic properties or overcome bacterial resistance.
• Academic Research: A valuable tool for universities and research institutes studying advanced organic synthesis and natural product chemistry.

Basic Information

Product Name	Ristomycin A aglycone, 34-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-2-deoxy-2-(10-methyl-1-oxoundecyl)amino-β-D-glucopyranosyl-42-O-α-D-mannopyranosyl-
CAS No.	122068-02-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	22,31-Dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosylristomycin A aglycone 34-O-(2-acetamido-2-deoxy-β-D-glucopyranoside); Ristomycin A derivative, 34-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-; Modified Ristomycin A Aglycone; CAS 122068-02-4
EINECS	Contact for details

Quality Control

Our Ristomycin A aglycone derivative is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is accompanied by comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.