Description

Sodium (6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate pentahydrate is a high-purity, semi-synthetic cephalosporin derivative designed for advanced pharmaceutical research and development. This compound is critical for its potent antibacterial activity, particularly against a broad spectrum of β-lactamase-producing organisms. It serves as a key active pharmaceutical ingredient (API) intermediate for manufacturers and research institutions focused on next-generation antibiotic therapies.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Primary use as a crucial intermediate in the manufacturing of advanced cephalosporin antibiotics.
• Pharmaceutical Research & Development: Serves as a reference standard and building block in drug discovery programs targeting resistant bacterial infections.
• Antibacterial Agent Development: Used in preclinical and clinical studies to develop new formulations with enhanced efficacy and stability.
• Analytical Standard: Employed in quality control laboratories for method development, validation, and assay calibration.
• Chemical Synthesis: Acts as a specialized intermediate for synthesizing novel β-lactam compounds and studying structure-activity relationships (SAR).

Basic Information

Item	Detail
Product Name	Sodium (6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate pentahydrate
CAS No.	115850-11-8
Molecular Formula	C16H15N9NaO6S2 • 5H2O
Molecular Weight	Contact for details
Synonyms	Cefmenoxime Sodium Salt Pentahydrate; SCE-1365; SCE 1365; SCE1365; (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt; Cefmenoxime Hemihydrochloride (common misnomer); Antibiotic SCE-1365; Tacef
EINECS	Contact for details

Quality Control

Our sodium (6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate pentahydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure compliance with pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under controlled conditions to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	10.0% - 15.0% (Theoretical for pentahydrate ~13.6%)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.