Description

7-(((-7-(2-(2-Amino-4-thiazolyl)-2-((1-(3-(3,4-dihydroxybenzoyl)carbazoyl)-1-methylethoxy)imino)acetamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)thio-5-methyl)-(1,2,4)triazolo(1,5-1)pyrimidine-2-carboxylic acid is a sophisticated cephalosporin-based advanced intermediate with a complex molecular architecture designed for high biological activity. Its value lies in its role as a critical building block for the synthesis of novel, potent antibacterial agents, particularly within the β-lactam class. This compound is essential for pharmaceutical R&D teams and manufacturers focused on developing next-generation antibiotics to address evolving microbial resistance.

Application

• Pharmaceutical Active Ingredient (API) Synthesis: Serves as a key intermediate in the production of advanced cephalosporin antibiotics.
• Antibacterial Drug Research & Development: Used in medicinal chemistry for designing and testing new compounds against resistant bacterial strains.
• Biochemical Research: Employed in studies investigating the structure-activity relationship (SAR) of β-lactam antibiotics.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical manufacturing.
• Preclinical Studies: Acts as a starting material or intermediate for compounds in pharmacological and toxicological evaluation.

Basic Information

Product Name	7-(((-7-(2-(2-Amino-4-thiazolyl)-2-((1-(3-(3,4-dihydroxybenzoyl)carbazoyl)-1-methylethoxy)imino)acetamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)thio-5-methyl)-(1,2,4)triazolo(1,5-1)pyrimidine-2-carboxylic acid
CAS No.	115761-49-4
Molecular Formula	C32H30N12O9S3
Molecular Weight	822.85 g/mol
Synonyms	(6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-[[(2S)-2-[[(3,4-Dihydroxybenzoyl)amino]methyl]-1,1-dimethyl-2-oxoethoxy]imino]acetyl]amino]-3-[[5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cephalosporin intermediate 115761-49-4; 7-ACA derivative with triazolopyrimidine; Advanced β-lactam intermediate; Antibiotic synthesis intermediate CAS 115761-49-4
EINECS	Contact for details

Quality Control

Our production of this high-purity pharmaceutical intermediate adheres to stringent quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and Mass Spectrometry to ensure structural identity and purity. We provide comprehensive Certificates of Analysis (COA) detailing all critical parameters, supporting compliance with cGMP guidelines for API manufacturing. Specifications can be aligned with client-specific pharmacopeial or internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.