Description

Furo[2,3-h]pyrrolo[3,2,1-jk][1]benzazepin-10(4H)-one, 8-ethyl-5,6,7,7a,8,8a,11,11a-octahydro-11-methyl-2-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]- (7aR,8R,8aS,11S,11aR)- is a complex, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. Its intricate fused-ring structure makes it a valuable key intermediate for the research and development of novel pharmacologically active molecules. This high-purity building block is primarily sought by pharmaceutical R&D teams and contract research organizations (CROs) working on next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing novel chemical libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for studies in synthetic methodology, asymmetric synthesis, and heterocyclic chemistry.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or molecular probes for biochemical and pharmacological assays due to its functionalizable core.

Basic Information

Product Name	Furo[2,3-h]pyrrolo[3,2,1-jk][1]benzazepin-10(4H)-one, 8-ethyl-5,6,7,7a,8,8a,11,11a-octahydro-11-methyl-2-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-, (7aR,8R,8aS,11S,11aR)-
CAS No.	106861-40-9
Molecular Formula	C22H29NO4
Molecular Weight	371.47 g/mol
Synonyms	(7aR,8R,8aS,11S,11aR)-8-Ethyl-11-methyl-2-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-5,6,7,7a,8,8a,11,11a-octahydro-4H-furo[2,3-h]pyrrolo[3,2,1-jk][1]benzazepin-10-one; 106861-40-9; UNII-9V3F5489VZ; 9V3F5489VZ; SCHEMBL2180621; AOB67717; (7aR,8R,8aS,11S,11aR)-rel-8-Ethyl-11-methyl-2-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-4H,5H,6H,7H,7aH,8H,8aH,11H,11aH-furo[2,3-h]pyrrolo[3,2,1-jk][1]benzazepin-10-one
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with each batch to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.