Description

(3R,3aα,5aα,9aβ,11aα)-3β,3bβ-(Epoxymethano)-4α,5α,12-trihydroxy-3a,3b,4,5,5a,6,7,8,9,9a,9bα,10,11,11a-tetradecahydro-6,6,9a-trimethylphenanthro[1,2-c]furan-1(3H)-one 4-butyrate 5-acetate is a complex diterpenoid derivative, specifically a functionalized phenanthrofuranone, valued for its intricate molecular architecture. This compound serves as a critical advanced intermediate in the synthesis of high-value pharmaceutical and bioactive molecules. It is primarily sought by research institutions and pharmaceutical developers engaged in medicinal chemistry, process development, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex natural product analogs and potential drug candidates.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a benchmark or target molecule for developing scalable synthetic routes in API (Active Pharmaceutical Ingredient) manufacturing.
• Biochemical Research: Potential use as a probe or standard in studying biological pathways involving diterpenoid signaling.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	(3R,3aα,5aα,9aβ,11aα)-3β,3bβ-(Epoxymethano)-4α,5α,12-trihydroxy-3a,3b,4,5,5a,6,7,8,9,9a,9bα,10,11,11a-tetradecahydro-6,6,9a-trimethylphenanthro[1,2-c]furan-1(3H)-one 4-butyrate 5-acetate
CAS No.	106009-78-3
Molecular Formula	C₂₈H₃₈O₈
Molecular Weight	502.60 g/mol
Synonyms	Taxinine M 4,5-Diester; 4β,5α-Diacetoxy-2α,9α,10β,13α-tetraacetoxytaxa-4(20),11-dien; 4-Butyryl-5-acetyl taxinine M; 4-O-Butyryl-5-O-acetyltaxinine M; Phenanthro[1,2-c]furan-1(3H)-one, 3b,3b-(epoxymethano)-4,5,12-trihydroxy-3a,3b,4,5,5a,6,7,8,9,9a,9b,10,11,11a-tetradecahydro-6,6,9a-trimethyl-, 4-butyrate 5-acetate, (3R,3aα,4α,5α,5aα,9aβ,9bα,11aα)-; Taxusin derivative
EINECS	Contact for details

Quality Control

Our (3R,3aα,5aα,9aβ,11aα)-3β,3bβ-(Epoxymethano)-4α,5α,12-trihydroxy-3a,3b,4,5,5a,6,7,8,9,9a,9bα,10,11,11a-tetradecahydro-6,6,9a-trimethylphenanthro[1,2-c]furan-1(3H)-one 4-butyrate 5-acetate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the container to reach room temperature in a desiccator before opening to prevent condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.