Description

(αR,βS)-β-(BenzoylaMino)-α-[[(2,2,2-trichloroethoxy)carbonyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodeca is a complex, high-purity synthetic intermediate characterized by its specific stereochemistry and multiple protective groups. This compound is of significant value in advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents where precise molecular architecture is critical. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of complex active pharmaceutical ingredients (APIs), especially for oncology and anti-infective drugs.
• Process Chemistry Research: Used in route scouting and optimization studies to develop efficient and scalable synthetic pathways for target molecules.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore new chemical entities by modifying the core scaffold.
• Academics & Institutional R&D: Utilized in university and research institute laboratories for cutting-edge organic synthesis and methodology development.
• Custom Synthesis & Contract Manufacturing: A critical starting material or intermediate for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	(αR,βS)-β-(BenzoylaMino)-α-[[(2,2,2-trichloroethoxy)carbonyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodeca
CAS No.	100431-55-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(αR,βS)-β-(Benzoylamino)-α-[[(2,2,2-trichloroethoxy)carbonyl]oxy]benzenepropanoic Acid; CAS 100431-55-8; Benzoyl-protected amino acid derivative with Troc and acetyl groups; Complex dodecahydronaphthacene derivative; Stereospecific pharmaceutical intermediate; Multi-protected chiral synthon.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques such as HPLC, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the certificate of analysis. Keep the container in a dry, well-ventilated area. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.