Description

n-α-Boc-n-δ-Xanthyl-D-Glutamine is a specialized, high-purity protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in facilitating the controlled assembly of complex peptides and peptidomimetics, where the Boc (tert-butoxycarbonyl) and Xanthyl protecting groups offer orthogonal deprotection strategies. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, peptide-based drugs, and biochemical probes, where precise stereochemistry and functional group manipulation are paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of D-glutamine residues into peptide chains, enabling the study of structure-activity relationships.
• Pharmaceutical Research & Development: Serves as a crucial building block in the synthesis of potential drug candidates, particularly in oncology, neurology, and metabolic disease research.
• Peptidomimetic Design: Used to create non-natural peptide analogs with enhanced stability, bioavailability, or target specificity for therapeutic applications.
• Bioconjugation and Probe Development: Facilitates the site-specific labeling or functionalization of peptides and proteins for diagnostic and research purposes.
• Academic and Industrial Chemical Research: Employed in methodological studies exploring new synthetic routes and protecting group strategies in organic chemistry.

Basic Information

Product Name	n-α-Boc-n-δ-Xanthyl-D-Glutamine
CAS No.	990928-83-1
Molecular Formula	C₂₄H₂₈N₂O₆
Molecular Weight	440.49 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-N-δ-xanthyl-D-glutamine; Boc-D-Gln(Xan)-OH; (2R)-2-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]-5-(9H-xanthen-9-ylamino)-5-oxopentanoic acid; D-Glutamine, N2-[(1,1-dimethylethoxy)carbonyl]-N5-(9H-xanthen-9-yl)-; N-α-Boc-N-δ-xanthyl-D-glutamine; Boc-D-Glutamine(Xan); Protected D-Glutamine derivative; Xanthyl-protected Boc-D-Gln
EINECS	Contact for details

Quality Control

Our n-α-Boc-n-δ-Xanthyl-D-Glutamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.