Description

(R)-5-(Hydroxymethyl)-4-Methylmorpholin-3-One is a high-purity chiral morpholine derivative, a crucial building block in modern pharmaceutical synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with specific stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, antibacterial, and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Used as a building block in asymmetric catalysis and synthesis to introduce stereogenic centers into target molecules.
• Protease Inhibitor Development: Serves as a core structural component in the research and development of protease inhibitor类药物.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Process Chemistry: Utilized in the scale-up and optimization of synthetic routes for commercial pharmaceutical production.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	(R)-5-(Hydroxymethyl)-4-Methylmorpholin-3-One
CAS No.	960402-19-1
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	(R)-4-Methyl-5-(hydroxymethyl)morpholin-3-one; (3R)-5-(Hydroxymethyl)-4-methyl-3-morpholinone; (R)-4-Methyl-5-(hydroxymethyl)-3-morpholinone; (R)-HMM; Morpholin-3-one, 5-(hydroxymethyl)-4-methyl-, (3R)-; 960402-19-1; (R)-enantiomer of 5-(Hydroxymethyl)-4-methylmorpholin-3-one
EINECS	Contact for details

Quality Control

Our (R)-5-(Hydroxymethyl)-4-Methylmorpholin-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.