Description

tert-Butyl 2-(2-Chloroethyl)-2-Cyanopyrrolidine-1-Carboxylate is a high-value, multi-functional chemical intermediate featuring a protected pyrrolidine scaffold. This compound matters for its versatility in constructing complex nitrogen-containing heterocycles, which are pivotal in modern pharmaceutical and agrochemical discovery. It is primarily needed by research chemists and process development scientists in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides due to its functionalized pyrrolidine core.
• Chemical Research & Development: Serves as a versatile precursor in organic synthesis for creating libraries of novel heterocyclic compounds.
• Process Chemistry: Employed in route scouting and scale-up processes for the manufacture of advanced pharmaceutical intermediates.
• Protease Inhibitor Scaffolds: The structural motif is valuable in the design and synthesis of protease inhibitor candidates.

Basic Information

Product Name	tert-Butyl 2-(2-Chloroethyl)-2-Cyanopyrrolidine-1-Carboxylate
CAS No.	960294-12-6
Molecular Formula	C12H19ClN2O2
Molecular Weight	258.74 g/mol
Synonyms	1-Boc-2-(2-chloroethyl)-2-cyanopyrrolidine; 1-(tert-Butoxycarbonyl)-2-(2-chloroethyl)-2-cyanopyrrolidine; tert-Butyl 2-cyano-2-(2-chloroethyl)pyrrolidine-1-carboxylate; 2-(2-Chloroethyl)-2-cyano-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine; 2-Cyano-2-(2-chloroethyl)-1-N-Boc-pyrrolidine; 1-Boc-2-(2-chloroethyl)-2-cyanopyrrolidine; Pyrrolidine-1-carboxylic acid, 2-(2-chloroethyl)-2-cyano-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(2-Chloroethyl)-2-Cyanopyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.