Description

(1R,5R,6R,7S)-Rel-4-Oxo-8-(Phenylmethyl)-8-Azabicyclo[3.2.1]Oct-2-Ene-6,7-Dicarboxylicacid6,7-Dimethylester is a high-purity, advanced pharmaceutical intermediate with a complex, stereochemically defined bicyclic structure. This compound matters as a critical building block in the synthesis of sophisticated active pharmaceutical ingredients (APIs), where its precise stereochemistry is essential for biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and commercial synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities (NCEs) due to its rigid, functionalized scaffold.
• Process Chemistry & Scale-Up: Employed in the development of robust, scalable synthetic routes for API manufacturing under cGMP conditions.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in stereoselective transformations to construct molecules with high enantiomeric purity.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for client-specific API production projects.
• Academic Research: Used in university and institutional labs for studies in synthetic organic chemistry and methodology development.

Basic Information

Product Name	(1R,5R,6R,7S)-Rel-4-Oxo-8-(Phenylmethyl)-8-Azabicyclo[3.2.1]Oct-2-Ene-6,7-Dicarboxylicacid6,7-Dimethylester
CAS No.	960201-81-4
Molecular Formula	C20H21NO6
Molecular Weight	371.39 g/mol
Synonyms	8-Benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid 6,7-dimethyl ester; (1R,5R,6R,7S)-8-Benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid dimethyl ester; rel-(1R,5R,6R,7S)-8-Benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic Acid Dimethyl Ester; Bicyclic Tropane Derivative; 8-Azabicyclo[3.2.1]octane-6,7-dicarboxylic acid dimethyl ester derivative
EINECS	Contact for details

Quality Control

Our (1R,5R,6R,7S)-Rel-4-Oxo-8-(Phenylmethyl)-8-Azabicyclo[3.2.1]Oct-2-Ene-6,7-Dicarboxylicacid6,7-Dimethylester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and stereochemical purity suitable for advanced pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.