Description

(R)-1-Amino-8-(Diphenylphosphino)-1,2,3,4-Tetrahydronaphthalene, Min. 97% is a high-purity, chiral organophosphine ligand featuring a tetralin backbone. This compound matters as a sophisticated catalyst component, enabling highly selective transformations in asymmetric synthesis, which is critical for producing enantiomerically pure intermediates. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric hydrogenation reactions.
• For the synthesis of enantiomerically pure pharmaceutical intermediates, particularly in the development of central nervous system (CNS) and cardiovascular drugs.
• In asymmetric C-C and C-X bond-forming reactions, such as cross-couplings and allylic substitutions.
• As a key component in catalyst screening libraries for process chemistry and medicinal chemistry research.
• For the preparation of specialty fine chemicals and advanced materials requiring high stereochemical control.
• In academic and industrial research focused on methodology development for sustainable and efficient synthetic routes.

Basic Information

Product Name	(R)-1-Amino-8-(Diphenylphosphino)-1,2,3,4-Tetrahydronaphthalene, Min. 97%
CAS No.	960128-64-7
Molecular Formula	C22H22NP
Molecular Weight	331.39 g/mol
Synonyms	(R)-1-Amino-8-(diphenylphosphino)-1,2,3,4-tetrahydronaphthalene; (R)-8-(Diphenylphosphino)-1,2,3,4-tetrahydro-1-naphthylamine; (R)-1-NH2-8-PPh2-Tetralin; (R)-Amino-DPP-Tetralin; (R)-Tetralin-based aminophosphine ligand; (R)-1,2,3,4-Tetrahydro-8-(diphenylphosphino)-1-naphthalenamine; (R)-8-Diphenylphosphino-1,2,3,4-tetrahydro-1-naphthylamine
EINECS	Contact for details

Quality Control

Our (R)-1-Amino-8-(Diphenylphosphino)-1,2,3,4-Tetrahydronaphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure a minimum purity of 97% and high enantiomeric excess (ee). Certificates of Analysis (COA) with full analytical data are provided to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Enantiomeric Excess (HPLC)	Contact for details
Water Content (KF)	Contact for details
Residue on Ignition	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.