Description

2,4-Dibromothiazole is a high-purity brominated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactivity as a key intermediate in the construction of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those containing thiazole or substituted thiazole cores with potential biological activity.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the dibromothiazole moiety can impart specific modes of action.
• Material Science Research: Serves as a building block for creating specialized polymers, ligands for catalysis, and organic electronic materials due to its halogenated structure.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, enabling rapid diversification of molecular scaffolds.
• Chemical Library Development: Employed in high-throughput and parallel synthesis for generating diverse compound libraries for screening in drug discovery programs.

Basic Information

Product Name	2,4-Dibromothiazole
CAS No.	960069-34-5
Molecular Formula	C3HBr2NS
Molecular Weight	242.82 g/mol
Synonyms	2,4-Dibromo-1,3-thiazole; Thiazole, 2,4-dibromo-; 2,4-Dibromothiazole; 960069-34-5; Dibromothiazole; NSC 83616
EINECS	Contact for details

Quality Control

Our 2,4-Dibromothiazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.