Description

5-Bromo-3-Methyl-1,2,4-Oxadiazole is a versatile halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, where its unique oxadiazole core enables the introduction of critical functional groups. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the oxadiazole moiety.
• Material Science Precursor: Acts as a building block for creating specialized polymers, liquid crystals, and organic electronic materials with tailored properties.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse compound libraries.

Basic Information

Product Name	5-Bromo-3-Methyl-1,2,4-Oxadiazole
CAS No.	960053-90-1
Molecular Formula	C₃H₃BrN₂O
Molecular Weight	162.97 g/mol
Synonyms	3-Methyl-5-bromo-1,2,4-oxadiazole; 5-Bromo-3-methyl-[1,2,4]oxadiazole; 1,2,4-Oxadiazole, 5-bromo-3-methyl-; Oxadiazole, 5-bromo-3-methyl-1,2,4-; BRM3MO; 960053-90-1 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Methyl-1,2,4-Oxadiazole is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.