Description

2-Fluoro-5-(Isopropylcarbamoyl)Benzeneboronic Acid is a specialized organoboron compound that serves as a valuable synthetic intermediate. Its core value proposition lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a fluorinated aromatic ring and an amide moiety, enabling the construction of complex molecular architectures. This high-purity building block is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form biaryl and heterobiaryl structures central to many modern compounds.
• Chemical Biology Probes: Serves as a precursor for fluorescent tags or molecular probes used in biochemical assay development and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis organizations (CSOs) and CDMOs producing bespoke compounds for client R&D pipelines.

Basic Information

Product Name	2-Fluoro-5-(Isopropylcarbamoyl)Benzeneboronic Acid
CAS No.	874289-49-3
Molecular Formula	C10H13BFNO3
Molecular Weight	225.03 g/mol
Synonyms	[2-Fluoro-5-(propan-2-ylcarbamoyl)phenyl]boronic acid; 2-Fluoro-5-[(1-methylethyl)carbamoyl]benzeneboronic acid; 5-Borono-2-fluoro-N-isopropylbenzamide; 2-Fluoro-5-(isopropylaminocarbonyl)phenylboronic acid; B-[2-Fluoro-5-[(1-methylethyl)carbamoyl]phenyl]boronic acid; 874289-49-3; 2-Fluoro-5-isopropylcarbamoylbenzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Isopropylcarbamoyl)Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.