Description

5-Chlorothiazole-2-Sulfonyl Chloride is a high-purity, reactive organosulfur compound that serves as a critical building block in advanced chemical synthesis. Its dual functionality as a sulfonyl chloride and a halogenated heterocycle makes it an indispensable reagent for introducing the 5-chlorothiazole-2-sulfonyl moiety into target molecules. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, including potential enzyme inhibitors and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymes or receptors where the chlorothiazole-sulfonamide pharmacophore is desired.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Employed in the creation of specialized polymers, ligands for catalysis, or functional materials that require sulfonamide or thiazole linkages.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation or as a scaffold in designing chemical probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences.

Basic Information

Product Name	5-Chlorothiazole-2-Sulfonyl Chloride
CAS No.	959997-70-7
Molecular Formula	C3HCl2NO2S2
Molecular Weight	238.13 g/mol
Synonyms	2-Thiazolesulfonyl chloride, 5-chloro-; 5-Chloro-2-thiazolesulfonyl chloride; 5-Chloro-1,3-thiazole-2-sulfonyl chloride; 959997-70-7; 5-Chlorothiazole-2-sulphonyl chloride; 5-Chloro-thiazole-2-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Chlorothiazole-2-Sulfonyl Chloride is manufactured and analyzed under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, confirming compliance with agreed specifications. Our quality protocols are designed to meet the stringent requirements of GMP environments for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.