Description

4-Iodo-1-Methyl-1H-Pyrazole-5-Carbaldehyde is a versatile and highly functionalized heterocyclic building block. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research, due to its reactive aldehyde and halogenated pyrazole core. It is primarily sought after by research chemists and process development scientists in the life sciences sector for constructing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by serving as a core scaffold for bioactive molecules.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Useful for creating molecular probes to study biological pathways and protein interactions.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse compound libraries.
• Heterocyclic Chemistry: Serves as a fundamental building block for constructing more complex fused or polycyclic heterocyclic systems.

Basic Information

Product Name	4-Iodo-1-Methyl-1H-Pyrazole-5-Carbaldehyde
CAS No.	959986-66-4
Molecular Formula	C5H5IN2O
Molecular Weight	236.01 g/mol
Synonyms	1-Methyl-4-iodo-1H-pyrazole-5-carboxaldehyde; 4-Iodo-1-methyl-1H-pyrazole-5-carboxaldehyde; 1-Methyl-4-iodopyrazole-5-carbaldehyde; 5-Formyl-1-methyl-4-iodopyrazole; 959986-66-4; 4-Iodo-1-methylpyrazole-5-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4-Iodo-1-Methyl-1H-Pyrazole-5-Carbaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical production, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.