Description

Zolpidem-D6 (Not Suitable For Use With Gc/Ms) is a stable isotope-labeled analog of the sedative-hypnotic agent Zolpidem, where six hydrogen atoms are replaced by deuterium. This high-purity reference material is essential for ensuring the accuracy and reliability of quantitative analyses in pharmaceutical research and development. It is primarily used by analytical laboratories and pharmaceutical companies engaged in method development, quality control, and metabolism studies for sedative drugs, where precise internal standardization is critical.

Application

• As a stable isotope-labeled internal standard for the precise quantification of Zolpidem in biological matrices using Liquid Chromatography-Mass Spectrometry (LC-MS/MS).
• For pharmacokinetic and metabolism studies to track the absorption, distribution, metabolism, and excretion of Zolpidem.
• In the development and validation of analytical methods for pharmaceutical quality control and forensic toxicology.
• Supporting bioequivalence and clinical studies where accurate measurement of drug concentration is required.
• Used in research focused on drug-drug interactions and metabolic pathway elucidation.

Basic Information

Product Name	Zolpidem-D6 (Not Suitable For Use With Gc/Ms)
CAS No.	959605-90-4
Molecular Formula	C19H15D6N3O
Molecular Weight	314.40 g/mol
Synonyms	Zolpidem-d6; Deuterated Zolpidem; N,N,6-Trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide-d6; Ambien-d6; Stilnox-d6; N,N-Dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide-d6
EINECS	Contact for details

Quality Control

Our Zolpidem-D6 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and isotopic purity, meeting the exacting standards required for reference materials. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as assay, isotopic enrichment, and impurity profile. We support compliance with GMP/GLP guidelines for research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (Mass Spectrometry)	Conforms
Assay (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98.0 atom % D
Chemical Purity (HPLC)	≥ 98.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.