Description

(2-[3-Methyl-5-(Trifluoromethyl)-1H-Pyrazol-1-Yl]-1,3-Thiazol-4-Yl)Methanol is a high-value, heterocyclic organic compound featuring a pyrazole-thiazole core functionalized with a trifluoromethyl group and a hydroxymethyl moiety. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for modern agrochemical and material science research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients. The compound's properties are leveraged to enhance the biological activity, metabolic stability, and physicochemical profile of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated heterocycles.
• Agrochemical Research: Serves as a building block for next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group often confers improved efficacy and environmental profile.
• Material Science Precursor: Used in the synthesis of specialized ligands, catalysts, and organic electronic materials due to its rigid, electron-deficient heterocyclic system.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a fragment in fragment-based drug discovery (FBDD).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	(2-[3-Methyl-5-(Trifluoromethyl)-1H-Pyrazol-1-Yl]-1,3-Thiazol-4-Yl)Methanol
CAS No.	959582-07-1
Molecular Formula	C9H8F3N3OS
Molecular Weight	263.24 g/mol
Synonyms	4-(Hydroxymethyl)-2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole; 1,3-Thiazole-4-methanol, 2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-; (2-(3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazol-4-yl)methanol; 959582-07-1; Pyrazole-thiazole methanol derivative; Trifluoromethyl pyrazolyl thiazole methanol
EINECS	Contact for details

Quality Control

Every batch of (2-[3-Methyl-5-(Trifluoromethyl)-1H-Pyrazol-1-Yl]-1,3-Thiazol-4-Yl)Methanol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles via HPLC, NMR, and MS are supplied with each shipment. Our quality commitment supports development from milligram to kilogram scale with consistent, reliable results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to strong alkali and fluorides; keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.