Description

(S)-2-Amino-3-(2-Carbamoylphenyl)Propanoic Acid is a non-natural, chiral amino acid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral building block and intermediate for the synthesis of novel, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for developing enzyme inhibitors, peptide mimetics, and other therapeutic agents targeting the central nervous system and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in neurology and metabolic disease.
• Peptidomimetic Design: Used to construct constrained peptide analogs and mimetics to enhance metabolic stability and bioavailability of drug candidates.
• Enzyme Inhibitor Synthesis: Serves as a core scaffold for designing potent and selective inhibitors of proteases and other enzymes.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and probes for studying biological pathways and target engagement.
• Asymmetric Catalysis Ligand Precursor: Can be utilized to develop novel chiral ligands for asymmetric synthesis.
• Academic & Contract Research: Essential for fundamental research in medicinal chemistry and organic synthesis at universities and CROs.

Basic Information

Product Name	(S)-2-Amino-3-(2-Carbamoylphenyl)Propanoic Acid
CAS No.	959581-86-3
Molecular Formula	C10H12N2O3
Molecular Weight	208.21 g/mol
Synonyms	(S)-2-Amino-3-(2-carbamoylphenyl)propanoic acid; (S)-2-Amino-3-(2-carbamoylphenyl)propionic acid; (S)-2-Amino-3-(2-carboxamidophenyl)propanoic acid; (S)-2-Amino-3-(2-aminocarbonylphenyl)propanoic acid; L-2-Amino-3-(2-carbamoylphenyl)propanoic acid; (S)-2-Amino-3-(o-carbamoylphenyl)propanoic acid; (S)-α-Amino-o-(aminocarbonyl)benzenepropanoic acid
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-3-(2-Carbamoylphenyl)Propanoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chiral excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.