Description

Fmoc-(R)-3-Amino-3-(6-Methoxy-3-Pyridyl)-Propionic Acid is a high-purity, non-natural amino acid derivative featuring an Fmoc-protected amine group and a pyridyl side chain. This compound is essential for the solid-phase peptide synthesis (SPPS) of peptides containing complex, heterocyclic residues, enabling the creation of novel peptide-based therapeutics and research tools. It is a critical building block for pharmaceutical R&D, particularly in the development of targeted drug candidates and diagnostic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of complex peptides.
• Pharmaceutical Research: Used in the discovery and development of novel peptide drugs, including enzyme inhibitors and receptor agonists/antagonists.
• Bioconjugation: Serves as a linker or modified residue for attaching peptides to other molecules, surfaces, or carriers.
• Chemical Biology Probes: Incorporated into peptides to study protein-protein interactions and cellular signaling pathways.
• API Intermediate: Acts as a chiral building block in the synthesis of active pharmaceutical ingredients (APIs).
• Academic & Contract Research: Utilized in university and CRO laboratories for fundamental peptide science and custom synthesis projects.

Basic Information

Product Name	Fmoc-(R)-3-Amino-3-(6-Methoxy-3-Pyridyl)-Propionic Acid
CAS No.	959581-71-6
Molecular Formula	C24H22N2O5
Molecular Weight	418.44 g/mol
Synonyms	Fmoc-(R)-3-Amino-3-(6-methoxypyridin-3-yl)propanoic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-3-(6-methoxy-3-pyridinyl)propanoic Acid; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-methoxypyridin-3-yl)propanoic Acid; Fmoc-(R)-Ampa(6-MeO-3-Pyridyl)-OH; Fmoc-(R)-3-(6-Methoxy-3-pyridyl)-alanine; Fmoc-R-3-Amino-3-(6-methoxy-pyridin-3-yl)-propionic acid
EINECS	Contact for details

Quality Control

Our Fmoc-(R)-3-Amino-3-(6-Methoxy-3-Pyridyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.