Description

n-Fmoc-L-2-Aminophenylpentanioc Acid is a sophisticated, non-natural amino acid derivative featuring a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group on the amine and a carboxylic acid functionality. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of modified amino acid residues into complex peptide chains. It is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require high-purity, specialized intermediates for creating novel peptide-based therapeutics, diagnostics, and biomaterials.

Application

• Solid-Phase Peptide Synthesis (SPPS): Primary use as a protected amino acid building block for the automated synthesis of custom peptides.
• Pharmaceutical Research & Development: Incorporation into peptide drug candidates to study structure-activity relationships (SAR) and develop new therapeutics.
• Bioconjugation & Probe Development: Used to create peptide tags, fluorescent probes, or affinity ligands for biochemical and diagnostic applications.
• Material Science: Serves as a monomer for constructing peptide-based polymers, hydrogels, and surface coatings with specific biological functions.
• Chemical Biology Studies: Enables the site-specific introduction of aromatic, non-proteinogenic side chains to modulate peptide stability, solubility, and receptor binding.
• Academic & Institutional Research: A key reagent for laboratories investigating peptide chemistry, medicinal chemistry, and protein engineering.

Basic Information

Product Name	n-Fmoc-L-2-Aminophenylpentanioc Acid
CAS No.	959578-11-1
Molecular Formula	C27H25NO5
Molecular Weight	443.49 g/mol
Synonyms	Fmoc-2-Amino-5-phenylpentanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-amino-5-phenylpentanoic acid; Fmoc-L-homoPhe(2-NH2)-OH; Fmoc-2-NH2-hPhe-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-phenylpentanoic acid; N-α-Fmoc-2-amino-5-phenylvaleric acid; Fmoc-2-Aminopentanoic acid, 5-phenyl-; Protected amino acid derivative CAS 959578-11-1
EINECS	Contact for details

Quality Control

Our n-Fmoc-L-2-Aminophenylpentanioc Acid is manufactured under strict quality control protocols to ensure the high purity and consistency required for sensitive research and production applications. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain stability. Keep container tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.