Description

(2S,4S)-4-(Furan-2-Ylmethyl)Pyrrolidine-2-Carboxylic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a stereochemically defined pyrrolidine core. This compound is a critical chiral building block and intermediate in modern pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs) and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, enzyme modulators, and other biologically active compounds.
• Peptidomimetics & Drug Discovery: Used to construct constrained peptide analogs and macrocyclic structures to improve metabolic stability and binding affinity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis and organocatalysis.
• Chemical Biology Research: Employed in the development of molecular probes and tool compounds for studying biological pathways.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for target molecules under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	(2S,4S)-4-(Furan-2-Ylmethyl)Pyrrolidine-2-Carboxylic Acid
CAS No.	959575-43-0
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	(2S,4S)-4-(2-Furanylmethyl)-2-pyrrolidinecarboxylic acid; (2S,4S)-4-(Furan-2-ylmethyl)pyrrolidine-2-carboxylic acid; 4-(Furan-2-ylmethyl)-L-proline; (2S,4S)-4-(2-Furylmethyl)pyrrolidine-2-carboxylic acid; 4-(2-Furylmethyl)-L-proline; (S,S)-4-(Furan-2-ylmethyl)pyrrolidine-2-carboxylic acid; Furan-2-ylmethyl-L-proline derivative
EINECS	Contact for details

Quality Control

Our (2S,4S)-4-(Furan-2-Ylmethyl)Pyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry, to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting research and development under quality-by-design (QbD) principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.