Description

Boc-L-2-Carbamoylphe is a protected amino acid derivative, specifically a Boc-protected phenylalanine analog with a carbamoyl substituent. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including protease inhibitors and bioactive peptide libraries. Its high purity and defined stereochemistry make it essential for advanced medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide-based drugs and protease inhibitors.
• Peptide Chemistry Research: Building block for solid-phase and solution-phase peptide synthesis (SPPS) to introduce modified phenylalanine residues.
• Medicinal Chemistry: Used in the design and development of peptidomimetics and constrained peptides for target validation and lead optimization.
• Bioconjugation: Potential reagent for creating peptide-linker constructs in antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Incorporation into peptide probes for studying enzyme-substrate interactions and protein function.
• Academic & Industrial R&D: Fundamental research tool in universities and corporate labs for exploring new synthetic methodologies and bioactive compounds.

Basic Information

Product Name	Boc-L-2-Carbamoylphe
CAS No.	959573-27-4
Molecular Formula	C15H20N2O5
Molecular Weight	308.33 g/mol
Synonyms	(2S)-2-{[(tert-Butoxy)carbonyl]amino}-3-(2-carbamoylphenyl)propanoic acid; Boc-2-Carbamoyl-L-phenylalanine; N-(tert-Butoxycarbonyl)-2-carbamoyl-L-phenylalanine; Boc-L-2-Carbamoylphenylalanine; tert-Butyl (2S)-2-amino-1-hydroxy-3-(2-carbamoylphenyl)-1,3-dioxopropan-2-ylcarbamate (alternative representation); Boc-Cpa(2-CONH2)-OH; Fmoc/Boc protected amino acid derivative; Chiral phenylalanine analog
EINECS	Contact for details

Quality Control

Our Boc-L-2-Carbamoylphe is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.