Description

5-Bromo-2-tert-Butylthiazole is a high-purity, versatile brominated heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a sterically hindered tert-butyl group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides, herbicides, and fungicides, leveraging its halogenated thiazole core.
• Ligand and Catalyst Development: Employed as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Acts as a monomer or functional additive in the development of advanced polymers, liquid crystals, and electronic materials.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	5-Bromo-2-tert-Butylthiazole
CAS No.	959240-27-8
Molecular Formula	C7H10BrNS
Molecular Weight	220.13 g/mol
Synonyms	2-tert-Butyl-5-bromothiazole; 5-Bromo-2-(1,1-dimethylethyl)-1,3-thiazole; 2-(tert-Butyl)-5-bromothiazole; 5-Bromo-2-(tert-butyl)thiazole; 959240-27-8; Thiazole, 5-bromo-2-(1,1-dimethylethyl)-; 5-Bromo-2-tert-butyl-thiazole
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-tert-Butylthiazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.