Description

Benzyl 3-(Hydroxymethyl)-4-Methylpyrrolidine-1-Carboxylate is a high-purity, protected pyrrolidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and key intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used as a building block for developing novel pesticides and herbicides with specific stereochemical requirements.
• Ligand & Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics & Bioactive Molecules: The protected hydroxymethyl and carboxylate groups make it valuable for constructing peptidomimetic scaffolds and other bioactive compounds.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring high stereochemical purity and reliable scalability.

Basic Information

Product Name	Benzyl 3-(Hydroxymethyl)-4-Methylpyrrolidine-1-Carboxylate
CAS No.	959236-80-7
Molecular Formula	C14H19NO3
Molecular Weight	249.31 g/mol
Synonyms	1-Carbobenzyloxy-3-hydroxymethyl-4-methylpyrrolidine; 1-CBZ-3-Hydroxymethyl-4-methylpyrrolidine; Benzyl (3-(hydroxymethyl)-4-methylpyrrolidin-1-yl)carboxylate; 4-Methyl-3-(hydroxymethyl)pyrrolidine-1-carboxylic acid benzyl ester; 1-N-CBZ-3-Hydroxymethyl-4-methylpyrrolidine; (3-Hydroxymethyl-4-methyl-pyrrolidin-1-yl)-carboxylic acid benzyl ester; 959236-80-7; 1-Cbz-4-methyl-3-pyrrolidinemethanol
EINECS	Contact for details

Quality Control

Every batch of Benzyl 3-(Hydroxymethyl)-4-Methylpyrrolidine-1-Carboxylate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed with a focus on meeting the stringent requirements of pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.