Description

1-n-Boc-3-(4-Bromobenzyl) Piperidine-3-Carboxylic Acid CAS NO 959235-99-5 is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine carboxylic acid core with a bromobenzyl substituent. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) drugs and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs.
• Protease Inhibitor Synthesis: Used in the preparation of potential inhibitors for various enzymatic targets.
• Ligand and Receptor Modulator Development: Integral for creating molecules that interact with specific biological receptors.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.
• Academic Research: Employed in university and institutional labs for studying chemical biology and synthetic methodology.

Basic Information

Product Name	1-n-Boc-3-(4-Bromobenzyl) Piperidine-3-Carboxylic Acid
CAS No.	959235-99-5
Molecular Formula	C19H26BrNO4
Molecular Weight	412.32 g/mol
Synonyms	1-Boc-3-(4-Bromobenzyl)piperidine-3-carboxylic acid; tert-Butyl 3-(4-bromobenzyl)-3-carboxypiperidine-1-carboxylate; 3-[(4-Bromophenyl)methyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-3-carboxylic acid; 1-(tert-Butoxycarbonyl)-3-(4-bromobenzyl)piperidine-3-carboxylic acid; N-Boc-3-(4-Bromobenzyl)nipecotic acid; 959235-99-5; 1-Boc-3-(p-Bromobenzyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-n-Boc-3-(4-Bromobenzyl) Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production can align with research-grade to cGMP standards based on customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.