Description

1H-Imidazole-2-Carbonitrile, 4-(2-Aminoethyl)-5-Fluoro- is a high-value, fluorinated imidazole derivative, a key building block in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a reactive nitrile group, a primary amine, and a fluorine atom on an imidazole core, enabling the construction of complex pharmacophores. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in medicinal chemistry programs targeting CNS disorders and enzyme inhibition.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting kinase inhibition or requiring fluorinated heterocycles for improved metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the imidazole scaffold and fluorine atom contribute to biological activity.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for creating molecular probes and tool compounds used to study biological pathways and protein function.
• Material Science Precursor: Potential use in the synthesis of specialized ligands for catalysis or functionalized polymers with unique electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	1H-Imidazole-2-Carbonitrile, 4-(2-Aminoethyl)-5-Fluoro-
CAS No.	959234-28-7
Molecular Formula	C6H7FN4
Molecular Weight	154.15 g/mol
Synonyms	4-(2-Aminoethyl)-5-fluoro-1H-imidazole-2-carbonitrile; 5-Fluoro-4-(2-aminoethyl)-1H-imidazole-2-carbonitrile; 2-Cyano-4-(2-aminoethyl)-5-fluoroimidazole; 959234-28-7; 4-(2-Aminoethyl)-5-fluoroimidazole-2-carbonitrile; 5-Fluoro-4-(2-aminoethyl)imidazole-2-carbonitrile; Fluoro-aminoethyl imidazolecarbonitrile
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-2-Carbonitrile, 4-(2-Aminoethyl)-5-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.