Description

1H-Imidazole-5-Propanoic Acid, 2-Fluoro- is a high-value fluorinated imidazole derivative, a key building block in modern synthetic chemistry. Its core value lies in the strategic introduction of a fluorine atom onto the imidazole scaffold, which can dramatically alter the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require advanced intermediates for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides where the fluorine atom enhances bioavailability and environmental stability.
• Ligand & Catalyst Development: Serves as a sophisticated ligand precursor for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of specialty polymers, ionic liquids, and advanced organic electronic materials.
• Bioconjugation & Probe Chemistry: The carboxylic acid functionality allows for conjugation to biomolecules, useful in creating fluorescent probes or affinity tags.

Basic Information

Product Name	1H-Imidazole-5-Propanoic Acid, 2-Fluoro-
CAS No.	959092-31-0
Molecular Formula	C6H7FN2O2
Molecular Weight	158.13 g/mol
Synonyms	2-Fluoro-1H-imidazole-5-propanoic acid; 2-Fluoro-1H-imidazole-5-propionic acid; 2-Fluoroimidazole-5-propanoic acid; 2-Fluoro-5-(2-carboxyethyl)imidazole; 959092-31-0; 2-Fluoro-1H-imidazole-4-propanoic acid (tautomer); 2-Fluoro-3H-imidazole-4-propanoic acid
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-5-Propanoic Acid, 2-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.