Description

1H-Imidazole-5-Carboxylic Acid, 2-Fluoro-, Methyl Ester is a high-value fluorinated heterocyclic building block, a key intermediate in modern synthetic chemistry. Its core value lies in providing a functionalized imidazole scaffold that enables the precise introduction of fluorine and ester groups into target molecules, critical for modulating their physicochemical and biological properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients, particularly in the creation of enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated drug candidates, especially in oncology, antiviral, and anti-inflammatory research programs.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances bioavailability and environmental stability.
• Chemical Biology Probe Development: Serves as a precursor for creating labeled compounds and activity-based probes to study enzyme function and biological pathways.
• Material Science Research: Employed in the synthesis of specialty polymers and organic electronic materials that require tailored heterocyclic components.
• Custom Synthesis & Contract Manufacturing: A key starting material for fine chemical suppliers offering bespoke synthesis services for clients in life sciences.
• Academic & Institutional Research: Used in universities and research institutes for methodological development in fluorination chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	1H-Imidazole-5-Carboxylic Acid, 2-Fluoro-, Methyl Ester
CAS No.	959086-47-6
Molecular Formula	C5H5FN2O2
Molecular Weight	144.10 g/mol
Synonyms	2-Fluoro-1H-imidazole-5-carboxylic acid methyl ester; Methyl 2-fluoro-1H-imidazole-5-carboxylate; 2-Fluoro-1H-imidazole-5-carboxylic acid, methyl ester; 2-Fluoroimidazole-5-carboxylic acid methyl ester; Methyl 2-fluoroimidazole-5-carboxylate; 959086-47-6; 2-Fluoro-1H-imidazole-5-carboxylic acid methyl ester (CAS 959086-47-6)
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazole-5-Carboxylic Acid, 2-Fluoro-, Methyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or production specifications. Our quality system is designed to support cGMP and ISO standards for reliable, batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.