Description

1H-Imidazole-4-Carboxylic Acid, 5-Fluoro-, Methyl Ester is a high-value fluorinated imidazole derivative, a crucial building block in modern synthetic chemistry. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical companies engaged in the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, especially kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in developing novel fungicides and herbicides where the imidazole and fluorine moieties impart specific biological activity.
• Chemical Synthesis: Serves as a versatile building block for constructing more complex heterocyclic frameworks in medicinal and process chemistry.
• Material Science: Potential monomer or additive in the research of specialty polymers and advanced organic materials.
• Bioconjugation: The ester group can be utilized for further functionalization, making it useful in probe and linker chemistry for biochemical applications.

Basic Information

Product Name	1H-Imidazole-4-Carboxylic Acid, 5-Fluoro-, Methyl Ester
CAS No.	959028-01-4
Molecular Formula	C5H5FN2O2
Molecular Weight	144.10 g/mol
Synonyms	Methyl 5-fluoro-1H-imidazole-4-carboxylate; 5-Fluoro-1H-imidazole-4-carboxylic acid methyl ester; 5-Fluoroimidazole-4-carboxylic acid methyl ester; 4-Carbomethoxy-5-fluoroimidazole; 959028-01-4; 5-Fluoro-1H-imidazole-4-carboxylic acid, methyl ester
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-4-Carboxylic Acid, 5-Fluoro-, Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.