Description

1-Pyrrolidinecarboxylic Acid, 2-(1-Hydroxy-1-Methylethyl)-, Methyl Ester is a high-purity, specialized pyrrolidine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents and high-value intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its pyrrolidine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Research: Employed in medicinal chemistry to design and synthesize peptide analogs with improved stability and bioavailability.
• Fine Chemical Production: Acts as a versatile building block for the manufacture of complex, high-value specialty chemicals.
• Academic and R&D Laboratories: Utilized in exploratory synthetic chemistry for method development and novel compound library generation.

Basic Information

Product Name	1-Pyrrolidinecarboxylic Acid, 2-(1-Hydroxy-1-Methylethyl)-, Methyl Ester
CAS No.	959022-60-7
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	Methyl 2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate; 2-(1-Hydroxy-1-methylethyl)-1-pyrrolidinecarboxylic acid methyl ester; 2-(2-Hydroxypropan-2-yl)-N-methoxycarbonylpyrrolidine; L-tert-Leucine pyrrolidine methyl ester derivative; (S)-2-(1-Hydroxy-1-methylethyl)pyrrolidine-1-carboxylic acid methyl ester (if chiral); Proline tert-leucinol methyl ester analog
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxylic Acid, 2-(1-Hydroxy-1-Methylethyl)-, Methyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment where applicable, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.