Description

3H-1,2,4-Triazole-3-Thione, 2,4-Dihydro-4-(3-Methoxyphenyl)-5-[[5-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Methyl]- is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining triazole and pyrazole moieties. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for agrochemical and pharmaceutical applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe: Acts as a scaffold for designing enzyme inhibitors and receptor modulators in biochemical research.
• Material Science: Potential application in the synthesis of specialized polymers and ligands for metal-organic frameworks (MOFs).
• Contract Research & Development (CRO): Supplied to CROs for custom synthesis and medicinal chemistry programs.

Basic Information

Product Name	3H-1,2,4-Triazole-3-Thione, 2,4-Dihydro-4-(3-Methoxyphenyl)-5-[[5-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Methyl]-
CAS No.	958940-22-2
Molecular Formula	C15H14F3N5OS
Molecular Weight	369.37 g/mol
Synonyms	4-(3-Methoxyphenyl)-5-((5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)methyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione; 958940-22-2; 1,2,4-Triazole-3-thione derivative; 4-(3-Methoxyphenyl)-5-[(5-methyl-3-trifluoromethyl-1H-pyrazol-1-yl)methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione; 5-((5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)methyl)-4-(3-methoxyphenyl)-4H-1,2,4-triazole-3-thiol
EINECS	Contact for details

Quality Control

Our production of 3H-1,2,4-Triazole-3-Thione, 2,4-Dihydro-4-(3-Methoxyphenyl)-5-[[5-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Methyl]- adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.