Description

1-Cyclopropyl-1H-Benzo[D]Imidazole-2-Carbaldehyde Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 958863-44-0. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is essential for research and development chemists and manufacturers in the pharmaceutical and biotechnology sectors. The material's defined structure enables precise molecular construction for next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of proprietary drug candidates, especially in oncology and antiviral research.
• Chemical Synthesis Building Block: Used in medicinal chemistry for constructing complex benzimidazole-based heterocycles.
• Research & Development: Serves as a standard or starting material in academic and industrial R&D labs for studying structure-activity relationships (SAR).
• API Manufacturing: Employed in scale-up processes for the Good Manufacturing Practice (GMP) production of active pharmaceutical ingredients.
• Biochemical Research: Utilized in the development of enzyme inhibitors and receptor modulators due to its specific molecular framework.

Basic Information

Product Name	1-Cyclopropyl-1H-Benzo[D]Imidazole-2-Carbaldehyde Hydrochloride
CAS No.	958863-44-0
Molecular Formula	C11H11N2O·HCl
Molecular Weight	222.68 g/mol
Synonyms	1-Cyclopropyl-1H-benzimidazole-2-carboxaldehyde hydrochloride; 1-Cyclopropyl-2-formyl-1H-benzimidazole hydrochloride; 2-Formyl-1-cyclopropyl-1H-benzimidazole hydrochloride; 1-Cyclopropyl-1H-benzo[d]imidazole-2-carbaldehyde HCl; Benzimidazole-2-carbaldehyde, 1-cyclopropyl-, hydrochloride; 958863-44-0; 1-Cyclopropyl-1H-benzimidazole-2-carbaldehyde hydrochloride salt
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-1H-Benzo[D]Imidazole-2-Carbaldehyde Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can support development toward cGMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.