Description

(S)-Tetrahydro-1H-Oxazolo[3,4-A]Pyrazin-3(5H)-One is a high-purity chiral heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore novel bioactive molecules.
• Asymmetric Synthesis: Serves as a versatile scaffold for constructing enantiomerically pure compounds via various catalytic and stoichiometric methods.
• Agrochemical Development: Employed in the synthesis of novel, chiral crop protection agents and pesticides.
• Ligand and Catalyst Preparation: Utilized as a precursor for developing novel chiral ligands and organocatalysts.
• Academic & Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	(S)-Tetrahydro-1H-Oxazolo[3,4-A]Pyrazin-3(5H)-One
CAS No.	958693-53-3
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	(S)-Hexahydrooxazolo[3,4-a]pyrazin-3-one; (S)-3-Oxohexahydro-1H-oxazolo[3,4-a]pyrazine; (S)-1,4,6,7,8,8a-Hexahydro-3H-oxazolo[3,4-a]pyrazin-3-one; (S)-Tetrahydrooxazolopyrazinone; (S)-THOP; (S)-Oxazolopyrazinone; (3S)-Hexahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-3-one; (S)-Enantiomer of Oxazolopyrazine Scaffold
EINECS	Contact for details

Quality Control

Our (S)-Tetrahydro-1H-Oxazolo[3,4-A]Pyrazin-3(5H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for research and development applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.