Description

(S)-3-Amino-5-Methyl-2,3-Dihydrobenzo[B][1,4]Oxazepin-4(5H)-One Hcl is a high-purity, chiral benzoxazepine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate and a versatile building block for constructing complex molecules with potential biological activity. It is primarily sought after by R&D teams and process chemists in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic targets.
• Building Block for Medicinal Chemistry: Used in the design and synthesis of compound libraries for high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its defined (S)-configuration, enabling the production of enantiomerically pure compounds.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate in the development and optimization of scalable synthetic routes for candidate drugs.
• Chemical Biology Research: Employed as a probe or tool compound in biochemical and pharmacological research to study specific biological pathways.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-3-Amino-5-Methyl-2,3-Dihydrobenzo[B][1,4]Oxazepin-4(5H)-One Hydrochloride
CAS No.	958488-72-7
Molecular Formula	C11H13N3O2 • HCl
Molecular Weight	255.70 g/mol
Synonyms	(S)-3-Amino-5-methyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one hydrochloride; (S)-3-Amino-5-methyl-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-one HCl; 4(5H)-Benzoxazepin-4-one, 3-amino-2,3-dihydro-5-methyl-, hydrochloride, (3S)-; (S)-3-Amino-5-methyl-4,5-dihydro-3H-benzo[b][1,4]oxazepin-4-one hydrochloride; 958488-72-7; (S)-AMDBO HCl; (S)-enantiomer of 3-Amino-5-methyl-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-one hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-5-Methyl-2,3-Dihydrobenzo[B][1,4]Oxazepin-4(5H)-One Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess, ensuring compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.