Description

1-Bromo-3-(3-Fluoro-Propoxy)-Benzene is a high-purity aromatic ether building block featuring both bromine and fluorine substituents, offering versatile reactivity for advanced synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is essential for researchers and process chemists engaged in cross-coupling reactions, medicinal chemistry, and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Heck, and Buchwald-Hartwig amination reactions to form complex biaryl structures.
• Fluorine Chemistry Studies: Employed in academic and industrial R&D to study the effects of fluorine introduction on molecular properties like lipophilicity and metabolic stability.
• Contract Manufacturing & Custom Synthesis: Supplied to CDMOs for the production of client-specific compounds under cGMP or research-grade conditions.

Basic Information

Product Name	1-Bromo-3-(3-Fluoro-Propoxy)-Benzene
CAS No.	958454-26-7
Molecular Formula	C9H10BrFO
Molecular Weight	233.08 g/mol
Synonyms	3-(3-Fluoropropoxy)bromobenzene; 1-Bromo-3-(3-fluoropropoxy)benzene; Benzene, 1-bromo-3-(3-fluoropropoxy)-; 3-Bromophenyl 3-fluoropropyl ether; m-Bromo(3-fluoropropoxy)benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(3-Fluoro-Propoxy)-Benzene is manufactured under strict quality management systems. Each batch is analyzed using advanced techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications from research to commercial-scale cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.