Description

4-(tert-Butoxy)Benzotrifluoride, 97% Min. is a high-purity aromatic trifluoromethyl ether derivative, serving as a versatile and valuable building block in advanced organic synthesis. Its core value lies in the combination of the electron-donating tert-butoxy group and the electron-withdrawing trifluoromethyl group, which imparts unique reactivity and physicochemical properties to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and optoelectronic devices due to its stable aromatic structure.
• Polymer Science: Employed as a monomer or modifier to introduce fluorine-containing moieties into polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Functions as a protected phenol equivalent or a directing group in complex multi-step synthetic routes, including cross-coupling reactions.
• Material Science Research: Investigated for use in the development of novel coatings, adhesives, and advanced composite materials with specific performance requirements.

Basic Information

Product Name	4-(tert-Butoxy)Benzotrifluoride, 97% Min.
CAS No.	16222-44-9
Molecular Formula	C11H13F3O
Molecular Weight	218.22 g/mol
Synonyms	1-(tert-Butoxy)-4-(trifluoromethyl)benzene; p-(tert-Butoxy)benzotrifluoride; 4-(tert-Butyloxy)benzotrifluoride; 1-tert-Butoxy-4-(trifluoromethyl)benzene; α,α,α-Trifluoro-p-tert-butoxytoluene; 4-(1,1-Dimethylethoxy)benzotrifluoride; 4-(tert-Butoxy)α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 4-(tert-Butoxy)Benzotrifluoride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC/HPLC, NMR, and IR spectroscopy, to ensure a minimum purity of 97% and conformity to specified impurity profiles. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable batch-to-batch consistency for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	97.0% Min.
Water Content (KF)	0.5% Max.
Related Substances (GC/HPLC)	Total impurities: 3.0% Max.
Refractive Index	Contact for details
Density	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.