Description

Benzene, 1-Bromo-2,4,5-Trifluoro-3-Methoxy- is a highly functionalized aromatic building block, distinguished by its unique pattern of bromine, fluorine, and methoxy substituents. This compound is critical for advanced organic synthesis, offering precise control over molecular architecture in the development of complex, high-value molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) agents and anti-infectives.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure for creating advanced electronic materials due to its stable, substituted benzene ring and halogen atoms.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution, leveraging the reactive bromine site.
• Fluorine Chemistry Research: An essential reagent for studying structure-activity relationships (SAR) and introducing fluorine into complex molecules.
• Specialty Polymer Monomer: Potential use in synthesizing high-performance, fluorinated polymers with unique thermal and chemical resistance properties.

Basic Information

Product Name	Benzene, 1-Bromo-2,4,5-Trifluoro-3-Methoxy-
CAS No.	13332-24-6
Molecular Formula	C7H4BrF3O
Molecular Weight	241.01 g/mol
Synonyms	1-Bromo-2,4,5-trifluoro-3-methoxybenzene; 2,4,5-Trifluoro-3-methoxybromobenzene; 3-Bromo-2,4,5-trifluoroanisole; 2,4,5-Trifluoro-3-methoxyphenyl bromide; 3-Methoxy-2,4,5-trifluorobromobenzene; Bromo(trifluoro)methoxybenzene
EINECS	Contact for details

Quality Control

Our production of 1-Bromo-2,4,5-trifluoro-3-methoxybenzene adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.