Description

1-(3-Chloropropoxy)-4-Fluorobenzene is a versatile halogenated aromatic ether intermediate of significant importance in advanced organic synthesis. Its molecular structure, featuring both a reactive chloropropoxy side chain and a fluorobenzene core, makes it a valuable building block for constructing more complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Polymer Chemistry: Acts as a monomer or modifying agent in the production of specialty polymers with tailored properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions to introduce functionalized aromatic ether groups.
• Material Science Research: Utilized in developing advanced organic materials for optoelectronic and semiconductor applications.

Basic Information

Product Name	1-(3-Chloropropoxy)-4-Fluorobenzene
CAS No.	1716-42-3
Molecular Formula	C9H10ClFO
Molecular Weight	188.63 g/mol
Synonyms	4-Fluoro-1-(3-chloropropoxy)benzene; 1-Fluoro-4-(3-chloropropoxy)benzene; p-Fluorophenyl 3-chloropropyl ether; 3-Chloropropyl 4-fluorophenyl ether; 4-Fluorophenyl 3-chloropropyl ether; 1-Chloro-3-(4-fluorophenoxy)propane; (3-Chloropropoxy)fluorobenzene
EINECS	Contact for details

Quality Control

Our 1-(3-Chloropropoxy)-4-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases. Recommended storage temperature is 2-8°C for long-term stability, though the product is stable at room temperature for shorter periods. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.4980 - 1.5020
Density (20°C)	1.18 - 1.22 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.