Description

4-Bromo-2,3,5,6-Tetrafluoroanisole is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role in introducing both bromine and fluorine substituents into complex molecular architectures, enabling precise tuning of electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials in display and lighting technologies.
• Polymer Modification: Incorporated into specialty polymers to impart unique solubility, thermal stability, and surface properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Research & Development: A versatile reagent for exploring new reaction pathways and synthesizing complex fluorinated aromatic systems in academic and industrial labs.

Basic Information

Product Name	4-Bromo-2,3,5,6-Tetrafluoroanisole
CAS No.	1682-04-8
Molecular Formula	C7H3BrF4O
Molecular Weight	258.99 g/mol
Synonyms	1-Bromo-2,3,5,6-tetrafluoro-4-methoxybenzene; Anisole, 4-bromo-2,3,5,6-tetrafluoro-; 2,3,5,6-Tetrafluoro-4-bromoanisole; 4-Bromo-2,3,5,6-tetrafluoromethoxybenzene; p-Bromotetrafluoroanisole; Tetrafluorobromoanisole
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,3,5,6-Tetrafluoroanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment to guarantee supply consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.