Description

1-Fluoro-4-Methoxynaphthalene is a high-purity fluorinated naphthalene derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, combining a fluorine atom with a methoxy group on the naphthalene ring, makes it an essential intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications ranging from drug discovery to the development of functional organic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental persistence.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials and host molecules in OLED displays and lighting due to its favorable electronic properties.
• Liquid Crystal & Advanced Material Synthesis: Employed in the creation of fluorinated liquid crystals and other specialty polymers that require specific dielectric and optical characteristics.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl structures.
• Fluorine Chemistry Research: A valuable reference compound and starting material for academic and industrial research into new fluorination methodologies and the study of fluorine effects.

Basic Information

Product Name	1-Fluoro-4-Methoxynaphthalene
CAS No.	10471-09-7
Molecular Formula	C₁₁H₉FO
Molecular Weight	176.19 g/mol
Synonyms	4-Methoxy-1-fluoronaphthalene; 1-Fluoro-4-methoxynaphthalene; 4-Fluoro-1-methoxynaphthalene; 1-Fluoro-4-naphthyl methyl ether; NSC 406908; 1-Fluoro-4-methoxy-naphthalene
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-Methoxynaphthalene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and traceable quality supports your R&D and scale-up processes with confidence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.