Description

1-Bromo-2-(3-Fluoro-Propoxy)-Benzene is a high-purity, halogenated aromatic ether building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents on a benzene ring linked via a propoxy chain, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research and development chemists and process scale-up teams within the pharmaceutical and agrochemical industries. Its reliable quality and consistent supply are critical for accelerating drug discovery and material science projects.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations to form carbon-carbon and carbon-heteroatom bonds.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating specialized chemical libraries.
• Fluorine Chemistry Studies: A valuable substrate for investigating the effects of fluorine introduction on the physical and chemical properties of organic molecules.

Basic Information

Product Name	1-Bromo-2-(3-Fluoro-Propoxy)-Benzene
CAS No.	958454-22-3
Molecular Formula	C9H10BrFO
Molecular Weight	233.08 g/mol
Synonyms	2-Bromo-1-(3-fluoropropoxy)benzene; 1-Bromo-2-(3-fluoropropoxy)benzene; Benzene, 1-bromo-2-(3-fluoropropoxy)-; o-Bromo(3-fluoropropoxy)benzene; 3-Fluoropropyl 2-bromophenyl ether; 2-(3-Fluoropropoxy)bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-(3-Fluoro-Propoxy)-Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.