Description

3-Fluoro-4-(Methylthiomethoxy)Phenylboronic Acid is a specialized organoboron compound featuring a unique fluorinated and sulfur-containing aromatic structure. This boronic acid derivative is a critical building block in modern synthetic chemistry, enabling the formation of carbon-carbon bonds via the versatile Suzuki-Miyaura cross-coupling reaction. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the fluorine atom and thioether moiety can enhance biological activity and stability.
• Material Science Research: Serves as a monomer or building block for creating advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes, leveraging the boronic acid group's affinity for diols.
• Catalyst Ligand Synthesis: Used to prepare sophisticated ligand systems for transition metal catalysis in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CROs/CMOs developing proprietary compounds for clients.

Basic Information

Product Name	3-Fluoro-4-(Methylthiomethoxy)Phenylboronic Acid
CAS No.	958454-09-6
Molecular Formula	C8H10BFO3S
Molecular Weight	216.04 g/mol
Synonyms	[4-(Methylsulfanylmethoxy)-3-fluorophenyl]boronic acid; 3-Fluoro-4-(methylsulfanylmethoxy)benzeneboronic acid; (3-Fluoro-4-((methylthio)methoxy)phenyl)boronic acid; B-[3-Fluoro-4-[(methylthio)methoxy]phenyl]boronic acid; Boronic acid, B-[3-fluoro-4-[(methylthio)methoxy]phenyl]-; 958454-09-6; 3-Fluoro-4-(methylthiomethoxy)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Methylthiomethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.