Description

4-Fluoro-2-Methylsulfanylmethoxy-Benzeneboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Serves as a precursor for creating advanced polymers, liquid crystals, and organic electronic materials requiring specific fluorine-substituted aromatic structures.
• Chemical Research: A versatile reagent in academic and industrial laboratories for methodological development in palladium-catalyzed cross-coupling reactions.
• Custom Synthesis: Employed in contract research and manufacturing organizations (CROs/CMOs) for the bespoke production of complex, boronic acid-containing target molecules.

Basic Information

Product Name	4-Fluoro-2-Methylsulfanylmethoxy-Benzeneboronic Acid
CAS No.	958454-08-5
Molecular Formula	C8H10BFO3S
Molecular Weight	216.04 g/mol
Synonyms	2-[(Methylthio)methoxy]-4-fluorobenzeneboronic Acid; (4-Fluoro-2-((methylthio)methoxy)phenyl)boronic Acid; 4-Fluoro-2-(methylthiomethoxy)phenylboronic Acid; 958454-08-5; Benzeneboronic acid, 4-fluoro-2-[(methylthio)methoxy]-; 4-Fluoro-2-(methylsulfanylmethoxy)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methylsulfanylmethoxy-Benzeneboronic Acid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.