Description

4-(2-Fluoro-Ethylsulfanyl)-Benzeneboronic Acid is a specialized organoboron compound featuring a fluoroethylthio substituent, making it a valuable building block in modern synthetic chemistry. Its primary value lies in its dual functionality, where the boronic acid group enables Suzuki-Miyaura cross-coupling reactions, and the fluorinated thioether moiety can impart unique physicochemical properties to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery, especially for candidates targeting CNS disorders or requiring metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for synthesizing functionalized polymers, liquid crystals, or organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The boronic acid functionality makes it a direct participant in palladium-catalyzed C-C bond formation reactions to create biaryl structures.
• Chemical Biology Probes: Utilized in developing molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Fluorine Chemistry: Acts as a versatile scaffold for introducing fluorine-containing motifs into larger molecular architectures.

Basic Information

Product Name	4-(2-Fluoro-Ethylsulfanyl)-Benzeneboronic Acid
CAS No.	958451-96-2
Molecular Formula	C8H10BFO2S
Molecular Weight	200.04 g/mol
Synonyms	4-[(2-Fluoroethyl)thio]benzeneboronic Acid; Benzeneboronic acid, 4-[(2-fluoroethyl)thio]-; 4-(2-Fluoroethylsulfanyl)phenylboronic Acid; 4-(2-Fluoroethylthio)phenylboronic Acid; 4-(FEtS)PhB(OH)2; [4-(2-Fluoroethylsulfanyl)phenyl]boronic Acid; 4-(2-Fluoroethanethiol)benzeneboronic Acid
EINECS	Contact for details

Quality Control

Our production of 4-(2-Fluoro-Ethylsulfanyl)-Benzeneboronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for critical research and manufacturing applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, supporting compliance with internal quality standards and research documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.